| Avengers | Trade to Deplorables | RB David Montgomery (HOU), TE Sam LaPorta (DET), 5 FPs |
| Waive | TE Gunner Helm (TEN) |
| Move | RB Jacory Croskey-Merritt (WAS) [To IL], RB Josh Jacobs (GB) |
| Sign | TE Michael Mayer (LV) |
| Sign | WR Christian Kirk (SF) |
| Roughness | Sign | QB Kirk Cousins (LV) |
| Sign | RB Dameon Pierce (PHI) [2FP][Extra Pick] |
| Waive | WR Isaac TeSlaa (DET) |
| Move | QB Jalen Hurts (PHI) [To IR] |
| Deplorables | Waive | RB George Holani (SEA) |
| Move | WR Terry McLaurin (WAS) [To IR], RB Zach Charbonnet (SEA) |
| Trade to Dragons | WR Nico Collins (HOU) |
| Trade to Avengers | TE Colston Loveland (CHI), RB Josh Jacobs (GB), Week 7 Waiver Pick |
| EvilEmpire | Waive | RB Will Shipley (PHI) |
| Move | WR Ja'Kobi Lane (BAL) |
| Minutemen | Move | WR Davante Adams (LAR) [To IL] |
| Sign | DL Daron Payne (WAS) |
| Mayhem | Waive | QB Jameis Winston (NYG) |
| Move | WR A.J. Brown (NE) |
| Bruins | Trade to Dawgs | 1 FP |
| Waive | TE Cade Otton (TB), LB Patrick Queen (PIT) |
| Move | WR Roman Wilson (PIT) [To IL], DB Brian Branch (DET), WR Germie Bernard (PIT) [1FP] |
| Sign | DB Jacob Parrish (TB) |
| Sign | RB Seth McGowan (IND) |
| Dragons | Sign | QB J.J. McCarthy (NYG) [3FP] |
| Trade to Deplorables | LB Teddye Buchanan (BAL), RB Josh Jacobs (GB), 2027 2nd Round |
| Waive | RB Chris Brooks (GB), LB Tuli Tuipulotu (LAC) |
| Move | LB Henry To'oTo'o (HOU) |
| Dawgs | Trade to Bruins | Week 7 Waiver Pick |